The service I work in has very recently began collaboration in a pretty cool (pun intended) trial – the RINSE Trial (Rapid Infusion of Normal cold SalinE).
Why: Current guidelines only support the use of therapeutic hypothermia post ROSC (Return Of Spontaneous Circulation) – see the Australian Resuscitation Council (ARC) guidelines or the International Liaison Committee On Resuscitation (ILCOR) advisory statement. The RINSE trial was initiated to find out if there is any clinical benefit in commencing therapeutic hypothermia during resuscitation efforts by paramedics.
Background: Basically Therapeutic Hypothermia (TH) aims to slow the rate of metabolism down, reducing the body’s consumption of O2, and also lessening the chemical reactions that lead to reperfusion injury (reference). For a even more info on TH, visit the ever excellent Life In The Fast Lane and EMCrit.
How: Paramedics will be inducing TH by means of IV chilled Normal Saline, checking temperature via tympanic thermometers.
Who: This study is currently running in three states in Australia, by the three statewide Ambulance Services and a participating university in each of those states:
- Ambulance Victoria and Monash University
- South Australian Ambulance Service and Flinders University
- Western Australian Ambulance Service and University of Western Australia
Please check out the link for more and in-depth information!
RINSE trial ClinicalTrials.gov: http://clinicaltrials.gov/ct2/show/NCT01173393
Has your service implemented TH for cardiac arrest?